Room tenp: unacceptable; Refrigerated 4 days; Frozen: 1 month
Diagnose porphyrias: delta-ALA may be increased in attacks of acute intermittent porphyria, hereditary coproporphyria, and porphyria variegata; evaluation of certain neurological problems with abdominal pain; diagnosis of lead or mercury poisoning. Urinary delta-ALA is not a sensitive indicator of lead poisoning in children because it does not increase until blood lead concentration is 40 Âµg/dL, well above the recommended level of <15 Âµg/dL. ALA is increased also in tyrosinemia.1,2 Porphobilinogen and delta aminolevulinic acid are the tests of choice for acute intermittent porphyria. Recently the molecular lesions have been identified in a severely affected homozygote with delta aminolevulinate dehydratase deficient porphyria .