Specimen Requirements

Title

HELICOBACTER PYLORI IgA ANTIBODY

Specimen Requirement

SST or Red-Top

Methodology

ELISA

Stability

Room Temperature 72 hours; Refrigerated 72 hours; Frozen 7 days

Reference Range

By Report*

Turnaround

4-6 days Performed Sun-Sat

Clinical Use

Diagnose H pylori infection in patients with duodenal disease and for monitoring the eradication of H pylori following antimicrobial therapy; identify the small percentage of H pylori-infected patients who fail to mount a systemic IgG response and demonstrate IgA antibodies only and for those patients who have chronic mucosal infections Circulating antibodies to H pylori are predominantly of the IgG class. A systemic response of the IgA type is usually less pronounced but, if significant, may indicate a more severe inflammation. A few patients develop only antibodies to IgA. IgM antibodies are rarely found and appear to be of minor importance.

Test Code

HPIAW