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Specimen Requirements

Title

5-NUCLEOTIDASE

Specimen Requirement

1 SST/1.0 mL serum. Spin and separate within 2 hours.

Methodology

Stability

ROOM TEMP 4 HOURS; REFRIGERATED 7 DAYS; FROZEN 14 DAYS

Reference Range

Turnaround

3-5 DAYS -- PERFORMED SUN-SAT

Clinical Use

Nucleotidase, 5′ (NTP) is a phosphatase enzyme that acts only on nucleoside 5′ phosphates, such as adenosine 5′ phosphate (AMP; adenylic acid). It is increased 2-6 times in hepatobiliary diseases in which there is intra- or extrahepatic interference with the secretion of bile. In skeletal diseases NTP increases in serum are rarely observed, so assays of NTP are valuable in differentiating between evaluations in alkaline phosphatase caused by hepatobiliary diseases and those caused by diseases of the skeletal system.

Test Code

5NUCW

Holiday Information

Garcia Lab will be closed Thursday, November 28, in observance of Thanksgiving. We will resume our regular schedule on Friday.

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