Specimen Requirements
Title
Amitriptyline (Elavil, Pamelor)
Specimen Requirement
Collect red top or lavender EDTA (gently invert 10 times) and send. Testing requires 1.0 mL serum or plasma.
Do not use SST/gel-barrier tube.
For therapeutic monitoring, collect specimen immediately prior to next dose unless specified otherwise.
Methodology
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
Stability
Room temp: 14 days, Refrigerated: 14 days, Frozen: 14 days
Reference Range
The reference range is determined by the performing laboratory and will show on the report.
Turnaround
2-5 days
Clinical Use
Evaluate toxicity; monitor therapeutic levels
Test includes: Amitriptyline and Nortriptyline
Test Code
AMIW