Specimen Requirements

Title

ANTI NEUTROPHIL CYTOPLASMIC AB (ANCA)

Specimen Requirement

Collect SST, after 30 minutes of clotting, promptly centrifuge and refrigerate. 1 mL serum required.

Methodology

Immunoassay (IA)

Stability

Room temp: 7 days, Refrigerated: 14 days, Frozen: 30 days

Reference Range

BY REPORT*

Turnaround

3 Days, Performed: Tue-Sat

Clinical Use

If the ANCA Screen is positive, it will reflex to C-ANCA Titer and/or P-ANCA Titer, and/or atypical P-ANCA Titer.

Testing for anti-neutrophil cytoplasmic antibodies (P-ANCA and or C-ANCA) has been found to be useful in establishing the diagnosis of suspected vascular diseases (e.g., crescentic glomerulonephritis, microscopic polyarteritis and churg-strauss syndrome), bowel disease (Crohn’s Disease, ulcerative colitis, primary sclerosing cholangitis, and autoimmune hepatitis) as well as with other autoimmune diseases (drug-induced lupus, SLE, Felty’s Syndrome).

Test Code

ANCAQ