Specimen Requirements
Title
Anti-Th/To Ab (RDL)
Specimen Requirement
Collect SST/1.0 mL serum, after 30 minutes of clotting, promptly centrifuge and send.
Alternate sample: Red top
Methodology
RIPA gel radiography
Stability
Room temp: 7 days, Refrigerated: 14 days, Frozen: 60 days
Reference Range
By Report*
Turnaround
14-21 days
Clinical Use
The Th/To antibodies are present in 10-19% of patients with limited SSc, in 11% of patients with diffuse cutaneous SSc, and in 3% of patients with primary Raynaud’s disease. Anti-Th/To antibody has been shown to be highly specific for patients with SSc.
Test Code
THTO