Specimen Requirements


Anti-Thrombin III Activity

Specimen Requirement

2-Light Blue top tubes (sodium citrate 3.2%). Spin and separate plasma from cells within 4 hours of collection. Send frozen plasma in screw capped plastic vial; indicate on transport tube “plasma/lt blue”. Contact lab for dry ice for shipment.



Frozen 3 weeks

Reference Range

By Report*


1-3 Days

Clinical Use

Low levels of ATIII are associated with an increased risk of thrombosis. Acquired deficiencies frequently occur due to consumption in DIC, following major operations, in cases of nephrosis, in liver disease and in contraceptive use with estrogen. ATIII deficiency can cause heparin resistance.

Test Code