Specimen Requirements

Title

CA 15-3 (CANCER ANTIGEN 15-3)

Specimen Requirement

1 SST/2.0 mL serum. After 30 minutes of clotting, promptly centrifuge and refrigerate.

Frozen serum if testing cannot be performed within 24 hours.

Methodology

Stability

Refrigerated 24 hours; Frozen 7 days

Reference Range

By Report*

Turnaround

24 Hours

Clinical Use

Elevated serum CA 15-3 concentrations are found in 5% of stage I, 29% of stage II, 32% of stage III and 95% of stage IV carcinoma of the breast. Most (96%) patients with a CA 15-3 increase of greater than 25% have disease progression. Most (nearly 100%) patients with a CA 15-3 decrease of greater than 50% are responding to treatment.

Test Code

CA15M