Draw blood in a plain red-top tube/1.0 mL. Spin, separate and send refrigerated.
Alternate Specimen: Plasma/EDTA
Room Temperature 48 hours, Refrigerated 14 days, Frozen 14 days
Clozapine is an antipsychotic agent. Peak clozapine concentrations are reached in 1-6 hours following oral dosage. Elimination half-life is 4- 16 hours once steady state levels have been reached. Norclozapine has minimal therapeutic activity.