Specimen Requirements

Title

CREATINE KINASE-MB (CK-MB)

Specimen Requirement

1 SST/1.0 mL serum. After 30 minutes of clotting, promptly centrifuge and refrigerate.

Methodology

Stability

Refrigerated: 48 hours; Frozen: 3 months

Reference Range

By Report

Turnaround

1 day

Clinical Use

The quantitation of CK-MB levels in serum is used as an aid in the diagnosis of myocardial injury. Elevated CK-MB levels are associated with myocardial cell death and damage due to acute myocardial infarction (AMI). CK-MB levels can be detected as a result of myocardial injury within 3 to 8 hours following the onset of chest pain with peak concentrations being achieved within 12 to 24 hours and usually returning to baseline levels within 24 to 48 hours.

Test Code

CKMB