Specimen Requirements
Title
Anti-ENA Antibodies (ANTI-RNP/ANTI-Sm)
Specimen Requirement
Collect SST or red top/1 mL serum. If SST collected, allow to clot for 30 minutes, centrifuge and send refrigerated.
Methodology
Enzyme Linked Immunoassay
Stability
Room temp: 8 hours, Refrigerated: 7 days, Frozen: 14 days
Reference Range
By report*
Turnaround
1-3 days
Clinical Use
Detect antibodies associated with SLE and mixed connective tissue disease. Anti-Sm is highly specific for SLE. Anti-RNP is found with a variety of rheumatoid diseases with high titers associated mainly with MCTD
Test Code
ENAW