Specimen Requirements
Title
Factor IX Inhibitor Profile
Specimen Requirement
Collection Instructions:
Collect 2 light blue sodium citrate tubes, gently invert 10x, centrifuge and transfer 2.0 mL plasma to 2 separate screw top plastic vials, indicate on each plastic vial plasma/light blue and send frozen on dry ice.
Critical Frozen.
Patient Preparation:
Patient must not be receiving Coumadin (warfarin) or heparin therapy and patient fasting is preferred.
Methodology
F_9, 9BETH, F9_IS: Optical Clot-Based 9INHT: Technical Interpretation 9AINH: Medical Interpretation
Stability
Room temp: 4 hours, Refrigerated: 4 hours, Frozen:
Reference Range
The reference range is determined by the performing laboratory and will show on the report.
Turnaround
2-3 days performed Monday-Friday
Clinical Use
Testing begins with coagulation factor IX activity assay with dilutions to evaluate assay inhibition; if the factor IX activity assay is normal or increased, then a technical interpretation will be provided.
If the factor IX activity assay is decreased, then an inhibitor screen will be performed at an additional charge to look for specific factor IX inhibition and a professional interpretation will be provided. If specific inhibition is apparent, the titer of the inhibitor will be determined.
Test includes Factor IX Activity, do not order test code FAC9M with FAC9I.
Test Code
FAC9I