Specimen Requirements

Title

HLA-B27 Antigen

Specimen Requirement

Collect lavender EDTA or green top sodium heparin 1.0 mL minimum, send whole blood room temp.

Methodology

Flow Cytometry

Stability

Room temp: 7 days, Refrigerated: 5 days, Frozen: Unacceptable

Reference Range

By Report*

Turnaround

1-2 days, set up Monday-Saturday

Clinical Use

Evaluate spondylarthritis and other disorders associated with this antigen. Over 90% of ankylosing spondylitis (AS) patients, 75% of Reiter syndrome patients and 80% of patients with reactive arthritis (ReA) are HLA B27-positive.

Test Code

B27