Specimen Requirements
Title
LIVER-KIDNEY MICROSOMAL ANTIBODY
Specimen Requirement
1 SST/1.0 mL serum. After 30 minutes of clotting, promptly centrifuge and refrigerate.
Methodology
Stability
Refrigerated 21 days, Frozen 30 days
Reference Range
By Report*
Turnaround
4-DAYS --PERFORMED TUES,THURS,FRI
Clinical Use
The detection of LKM-1 Antibodies is an aid in the diagnosis of autoimmune hepatitis, type 2 (AIH2). LKM Antibodies are markers of AIH2 which usually begins in childhood and generally affects children under 18 years of age. LKM antibodies are associated with a more serious progression of the disease. The disease is most common between the ages of 2-14 and is more frequent in females than males (8:1). LKM-1 antibodies have been reported in up to 8% of patients with chronic HCV infection.
Test Code
LKMW