Liver-Kidney Microsome Antibody
Collect SST/1 mL serum, after 30 minutes of clotting, promptly centrifuge and send refrigerated.
Alternate sample: Red top
Enzyme Linked Immunoassay
Room temp: 8 hours, Refrigerated: 21 days, Frozen: 30 days
1-3 days, Performed Monday-Friday
The detection of LKM-1 Antibodies is an aid in the diagnosis of autoimmune hepatitis, type 2 (AIH2). LKM Antibodies are markers of AIH2 which usually begins in childhood and generally affects children under 18 years of age. LKM antibodies are associated with a more serious progression of the disease. The disease is most common between the ages of 2-14 and is more frequent in females than males (8:1). LKM-1 antibodies have been reported in up to 8% of patients with chronic HCV infection.