Specimen Requirements


Liver-Kidney Microsome Antibody

Specimen Requirement

Collect SST/1 mL serum, after 30 minutes of clotting, promptly centrifuge and send refrigerated.

Alternate sample: Red top


Enzyme Linked Immunoassay


Room temp: 8 hours, Refrigerated: 21 days, Frozen: 30 days

Reference Range

By Report*


1-3 days, Performed Monday-Friday

Clinical Use

The detection of LKM-1 Antibodies is an aid in the diagnosis of autoimmune hepatitis, type 2 (AIH2). LKM Antibodies are markers of AIH2 which usually begins in childhood and generally affects children under 18 years of age. LKM antibodies are associated with a more serious progression of the disease. The disease is most common between the ages of 2-14 and is more frequent in females than males (8:1). LKM-1 antibodies have been reported in up to 8% of patients with chronic HCV infection.

Test Code