Specimen Requirements


Lyme Disease Total AB with Reflex to IgG & IgM (Titer)

Specimen Requirement

Collect SST/2.0 mL serum, after 30 minutes of clotting, promptly centrifuge and send.

Alternate sample: Lavender EDTA or lithium heparin. If collecting lavender EDTA or lithium heparin, 2.0 mL plasma must be transferred to a screw top transport tube and sample type must be indicated on transport tube before sending.


Chemiluminescent Immunoassay (CLIA)


Room temp: 14 days, Refrigerated: 14 days, Frozen: 14 days

Reference Range

By report*


1-2 days

Clinical Use

This panel utilizes FDA-cleared assays following the modified 2-tier testing (MTTT) algorithm to aid in the diagnosis of Lyme disease in individuals with clinical signs and symptoms consistent with Lyme disease. Lyme disease should be considered based on the presence of typical signs and symptoms of infection in patients with a history of possible exposure to infected ticks.

Test Code