Specimen Requirements


Mitochondrial M2 Antibody

Specimen Requirement

Collect SST/1 mL serum. After 30 minutes of clotting, promptly centrifuge and send refrigerated.

Alternate sample:
Red top


Enzyme Linked Immunoassay


Room temp: 8 hours, Refrigerated: 48 hours, Frozen: 14 days

Reference Range

By Report*


1-3 days, Performed Mon-Fri

Clinical Use

Anti-Mitochondrial antibodies (AMA) have been reported in greater than 90% of patients with Primary Biliary Cirrhosis (PBC). AMA are also occasionally found in patients with chronic active hepatitis, cryptogenic cirrhosis and in patients with clinical but no biochemical evidence of liver disease. The M2 type of AMA is strongly associated with PBC.

Test Code