NS5A 1 HCV RNA GENOTYPE DRUG RESISTANCE
Preferred specimen is a full PPT, or 4mL plasma poured off from PPT.
Alternate specimen: Lavender or SST
**PLEASE DO NOT ORDER HCV GENOTYPE WITH THIS TEST IF YOU ALREADY KNOW THE GENOTYPE OF THE PATIENT. IT WILL DELAY TESTING.**
Polymerase chain reaction (PCR) amplification and DNA next generation sequencing (NGS)
Room Temperature: 72 hours; Refrigerated: 14 days; Frozen: 42 days
Assessment of drug susceptibility by nucleic acid sequencing of a patient’s hepatitis C virus (HCV) to the NS5A inhibitors. Detects resistance associated variants at positions 28, 30, 31, and 93 in genotype 1a HCV.
MUST HAVE GENOTYPE 1a or 1b!!!