Specimen Requirements

Title

OXCARBAZEPINE (10-HYDROXY CARBAZEPINE) (TRILEPTAL)

Specimen Requirement

Collect plain red top or lavender EDTA. Spin, separate 1.0 mL serum/plasma from cells within 2 hours and send in a plastic transport vial. Indicate specimen type on vial.

Do not use a gel-barrier tube.

 

Draw trough levels immediately prior to next dose. Steady-state levels are reached within two to three days in patients taking oxcarbazepine twice daily.

Methodology

Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Stability

Room temp: 14 days, Refrigerated: 14 days, Frozen: 105 days

Reference Range

By Report*

Turnaround

2-4 days Performed Mon-Fri

Clinical Use

Oxcarbazepine is an antiepileptic drug, indicated for use as monotherapy or adjunctive therapy in the treatment of partial seizures in adults with epilepsy. It is used in adjunctive therapy in epileptic children between the ages of four and 16.

Test Code

OXC