Specimen Requirements

Title

PROCAINAMIDE (INCLUDES METABOLITE N-ACETYLPROCAINAMIDE NAPA)

Specimen Requirement

1-plain red top/1.0 mL serum. Spin seperate and refrigerate.

DO NOT USE SST

Methodology

Stability

Room Temperature 4 days, Refrigerated 7 days

Reference Range

By Report*

Turnaround

3-5 days Performed Mon-Sat

Clinical Use

Monitoring of antiarrythmic drug level. Serum concentration peaks at 15-60 min following i.m. and 90-120 min following oral dosage. About 15-20% of Procainamide is bound reversibly to serum proteins. Elimination half-life is 3-4 hours in patients with normal renal function. It is longer in patients with decreased renal function and in the elderly. About 20% of the administered dose is metabolized to NAPA in the liver.

Test Code

PROCW