Specimen Requirements
Title
PROCAINAMIDE (INCLUDES METABOLITE N-ACETYLPROCAINAMIDE NAPA)
Specimen Requirement
1-plain red top/1.0 mL serum. Spin seperate and refrigerate.
DO NOT USE SST
Methodology
Stability
Room Temperature 4 days, Refrigerated 7 days
Reference Range
By Report*
Turnaround
3-5 days Performed Mon-Sat
Clinical Use
Monitoring of antiarrythmic drug level. Serum concentration peaks at 15-60 min following i.m. and 90-120 min following oral dosage. About 15-20% of Procainamide is bound reversibly to serum proteins. Elimination half-life is 3-4 hours in patients with normal renal function. It is longer in patients with decreased renal function and in the elderly. About 20% of the administered dose is metabolized to NAPA in the liver.
Test Code
PROCW