Specimen Requirements
Title
PROINSULIN
Specimen Requirement
Patient must fast 12-15 hours before collection.
Draw blood in a SST/1.0 mL serum. Spin, separate serum from cells within 2 hours and send refrigerated.
Alternate sample: Red top or lavender EDTA (must be poured off)
Methodology
Quantitative Chemiluminescent Immunoassay
Stability
Room temp: Unacceptable, Refrigerated: 48 hours, Frozen: 2 months
Reference Range
By Report*
Turnaround
3-7 days Performed Tues, Thurs
Clinical Use
To aid in the diagnosis of pancreatic beta cell dysfunction and proinsulinomas. Increased in IDDM and may also be increased in NIDDM patients. Levels are elevated in older patients, pregnant or obese diabetics, patients with functional hypoglycemia, insulinoma and hyperproinsulinoma.
Test Code
PINS