Specimen Requirements

Title

PROTEIN ELECTROPHORESIS, URINE RANDOM

Specimen Requirement

Collect first morning urine, send 20 mL in a sterile container, minimum 6 mL.

Preservative is not acceptable.

Methodology

Electrophoresis on agarose media

Stability

Room temp: Unacceptable, Refrigerated: 3 days, Frozen: 30 days

Reference Range

By Report*

Turnaround

3-5 days

Clinical Use

Evaluate myeloma, macroglobulinemia of Waldenström, lymphoma, amyloidosis; differentiate between normal renal function, glomerular proteinuria, and tubular proteinuria. Increased glomerular permeability leads to higher concentrations of large proteins in the glomerular filtrate. Diminished tubular reabsorptive capacity results in a marked increase in urinary excretion of low molecular weight problems.

Test Code

UPEMC