Specimen Requirements
Title
Prothrombin Gene Mutation (Factor II)
Specimen Requirement
Collect lavender EDTA, send whole blood room temp. Minimum 3 mL.
Alternate sample: yellow top ACD or LabCorp buccal swab kit
Methodology
Polymerase chain reaction (PCR); restriction enzyme digestion
Stability
Room temp: 5 days, Refrigerated/Frozen: Unacceptable
Reference Range
By Report*
Turnaround
5-7 days
Clinical Use
Contributes to the risk assessment for venous thromboembolis thromboembolism (VTE) to better inform decisions regarding treatment and clinical management decisions of patients with relevant personal history of VTE and potential preventative care for patients with significant family history of VTE.
Test Code
PTGW