Specimen Requirements

Title

Infliximab (Remicade), Quantitative w/ Reflex to AB

Specimen Requirement

Collect 1 mL serum from red top.

For 12 hours before specimen collection do not take supplements or vitamins containing biotin (vitamin B7).

Methodology

Selective Reaction Monitoring LC/MS-MS -- Reflexes to Electrochemiluminescent Bridging Immunoassay with Acid Dissociation

Stability

Room Temp: Unacceptable, Refrigerated: 28 days, Frozen: 28 days

Reference Range

By report*

Turnaround

5-8 days

Clinical Use

In the absence of anti-infliximab antibodies, the infliximab drug level typically reflects the total infliximab concentration in serum. In the presence of anti-infliximab antibodies, the infliximab drug level typically reflects the antibody-unbound fraction of infliximab concentration in serum.

Test Code

REMIC