Specimen Requirements

Title

THYROXINE-BINDING GLOBULIN (TBG)

Specimen Requirement

1 SST/1.0 mL serum. After 30 minutes of clotting, promptly centrifuge and refrigerate serum

Methodology

Stability

Room Temperature Unacceptable, Refrigerated 2 days, Frozen 14 days

Reference Range

By Report*

Turnaround

2 days Performed Mon-Fri

Clinical Use

Determine binding capacity for T4; document cases of hereditary deficiency of TBG, in work-up of thyroid disease, particularly in patients with low T4, high T3 (uptake) who clinically seem eumetabolic. Such patients may have hereditary anomalies of TBG and may not require treatment

Test Code

TBGW